Skin Sensitivity and Peeling Inside the Mouth

Our oral cavity is lined with a membrane called the mucosa. The mucus membranes provide a lining all over the inside of the mouth. Hence the skin inside the mouth is called oral mucosa. Whenever the mucous membranes get irritated, they encounter tissue sloughing. So skin inside the mouth, cheeks, back of the throat, palate, and inner lips will peel. Such skin peeling in the mouth is quite painful and is indicative of certain oral & systemic diseases. Sodium lauryl sulfate, sometimes known as "SLS," is a leading cause of inner cheek peeling.

Because of SLS's foaming effect, certain kinds of toothpaste have more bubbles and foam than others. SLS is irritating even on a small scale. Certain individuals are more vulnerable to skin irritation than others, and SLS is one of the worst offenders. Minor irritations to the mouth's lining often resolve on their own within a few days. Because of its ability to bind the other components of toothpaste, SLS is a standard component in many different formulations.

However, oral mucosa peeling is instigated by certain ingredients in substances we put in our mouths. Furthermore, skin peeling in the mouth is also connected to several physiological and skin conditions. They arise from habits like cheek biting, acidic substances in foods and drinks we intake, and so on. Likewise, taking hot foods also tends to peel off the oral mucosa. Meanwhile, it might be a side effect of dental complications like oral thrush. Our oral hygienists and dentists have compiled a list of the most likely causes of peeling skin in your mouth. However, oral mucosa peeling is instigated by certain ingredients in substances we put in our mouths. Furthermore, skin peeling in the mouth is also connected to several physiological and skin conditions. It should not be expected for the skin inside your mouth to flake after you have brushed your teeth.

The following are some of the possible reasons for skin peeling in the mouth −

  • oral skin response to drugs that you are taking;

  • an autoimmune illness that shows oral symptoms;

  • eating or drinking anything acidic that would burn the tissue;

  • a reaction to radiation treatment

A condition that may cause harmless tissue loss or mouth skin shedding at any age. This ailment is known as oral lichen planus.

Visiting an oral pathologist or experienced surgeon is the most beneficial thing you can do in this situation. Peeling skin almost always has an underlying reason. However, this does not imply that the problem is particularly significant. To identify who is responsible for what, someone must examine your mouth for the many systemic lesions. If your mouth is sensitive and inflamed, it is a good idea to use the softest toothbrush available and a very mild toothpaste, such as Tom's of Maine, which can be bought in most supermarkets. This will help reduce any further irritation that may occur.

In addition, I recommend that you gargle your mouth with a solution of warm salt water three or four times a day. This will help to bathe the tissues and make them feel better. However, for the issue to be dealt in the appropriate manner, you will need to consult with a trained specialist who can establish the root of the problem. If you want to feel better in the near term, treating the symptoms could help, but determining what's causing them is essential. Several factors might cause the skin to peel off in the mouth. It is hard to pinpoint without a dentist's help. Hence consult your dentist immediately once you notice chronic peeling skin in the mouth. Once the irritant is identified, your dentist will prescribe ways to adjust your routine to eliminate oral mucosa peeling.

What Causes the Skin Inside your Mouth to Peel?

Autoimmune Diseases

An autoimmune illness is a disorder in which the immune system of the affected individual's body attacks the affected individual's own body. The exact cause of this condition is still unknown. However, it is believed that some microorganisms confuse our natural defense system and cannot distinguish our cells from foreign cells. Around 80 types of autoimmune disorders are identified. Addison disease, Celiac disease are some examples. Once an autoimmune disease occurs, it shows warnings like inflamed glands, fatigue, skin problems like oral tissue sloughing, and so on.

SLS in Toothpaste

SLS – Sodium Lauryl Sulphate is an active ingredient in your toothpaste, regardless of its brand. It helps hold all ingredients in the toothpaste together and makes the toothpaste foamy. Even though SLS is a safe compound, it sometimes irritates the skin inside the mouth. Mouth sore sufferers and those with sensitive skin encounter annoyances like skin inside their mouth peeling off.

Stevens-Johnson Syndrome

Steven-Johnson Syndrome (SJS) is a rare autoimmune disorder affecting the skin and mucus membranes. When a person has SJS, it shows flu-like symptoms and is followed by a painful rash. Later the skin starts to blister and peel off. The upper body is where SJS typically begins to spread swiftly to the arms, legs, and other body regions.

SJS sufferers encounter more skin peeling off around their faces and tough sloughing inside their mouths.


Consistent intake of foods with low nutritional value will weaken your body. Because your body wouldn't receive the appropriate level of calories, vitamins, and minerals, various chronic diseases will occur. Likely, your skin health is also compromised by a poor diet. Research shows that falling short of Vitamins A, C, B3, B6, and B12, minerals, iron, and zinc will have detrimental effects on your skin. In such circumstances, the capacity of tissue healing inside the skin is reduced. You might notice unusual changes in your skin. Oral mucosa peeling is an example.

Food Allergies

Despite taking healthy & nutritious foods, certain ingredients irritate mucosa inside your mouth. Acidic substances are the main culprits to blame. They are powerful to cause rashes, redness, and even skin peeling in the mouth. Similar to the adverse effects of acidic compounds in foods we intake, our immune system exhibits allergic reactions like oral mucosa peeling after taking certain foods. Avoid including such foods in your diet plan whenever possible.

Updated on: 02-Feb-2023

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