Found 2 Articles for Agglutination

Introduction Agglutination is a type of antigen-antibody reaction where the antibody interacts with the particulate antigen which eventually gives us visible clumping. Here antigen is not soluble in the aqueous environment. Antibodies here are called agglutinins and antigens are called agglutinogens. Clumping is due to the cross-linking between a polyvalent antigen and agglutinins. RBC Agglutination Principle Antigens involved in the agglutination reaction are surface antigens present on erythrocytes, bacterial particles or antigens attached to some matrix. These particles involved in agglutination reaction should have multiple binding sites to form cross links resulting in clumping. To form a visible clumping ... Read More

Antibody specificity, or the capacity to bind to epitopes, is one of the key features of an antibody. Many different types of serological tests rely on this. Several bacteria and viruses can be identified by studying the reaction between an antibody and its associated antigen. Agglutination, precipitation, or activation of the complement system are all possible outcomes of this interaction. What is Agglutination? The process of agglutination involves the clustering of cells caused by the accumulation of antigens and antibodies. When an antibody binds to many antigens at once, bigger complexes are formed, which may then be seen. Particulate antigens ... Read More