Found 3 Articles for Genome

Difference Between Whole Genome Sequencing and Next Generation Sequencing

Vineet Nanda
Updated on 26-Apr-2023 16:15:58

115 Views

Our understanding of the human genome has grown tremendously over the last few decades, paralleled by the fast rise of sequence databases and bioinformatics tools. And the need to manufacture more, quicker, and cheaper DNA sequences has become critical for scientific inquiry. Advances in microarray technology enabled scientists and researchers to investigate the human genome with increasing resolution in the first decade of the twenty-first century. Traditional approaches have limits that need the creation of new experimental procedures. What is Whole Genome Sequencing? The full DNA sequence of a human, animal, plant, bacterial, or viral genome may be identified through ... Read More

Difference Between Genome Sequencing and Genome Mapping

Vineet Nanda
Updated on 26-Apr-2023 11:09:44

99 Views

Genome sequence and genome map are both engravings of a genome. Genome mapping is useful for pinpointing the location of and determining the proximity of individual genes. The Human Genome Project (HGP) is a worldwide scientific endeavour that can make use of this technique as a foundational first step. Low-resolution and high-resolution physical mapping, restriction enzymes as microscopic scalpels, genetic linkage maps, macro-restriction maps as a top-down approach, and contig maps as a bottom-up approach are all examples of mapping methods. Chromosome Isolation (Flow Sorting and Somatic Cell Hybridization) Genome sequencing is a technique for evaluating the whole deoxyribonucleic acid ... Read More

Reverse Transcriptase: Structure and Applications

Anusha Karthik
Updated on 31-Mar-2023 16:28:25

201 Views

Get to Know Reverse Transcriptase Reverse transcriptase is an RNA-dependent DNA polymerase that is capable of synthesizing a complementary DNA strand from an RNA template. The enzyme was first discovered in retroviruses, which are RNA viruses that use reverse transcriptase to convert their RNA genomes into DNA. Reverse transcriptase is also found in other retrotransposons, and telomerase, which are involved in maintaining the length of the chromosome ends. Structure Reverse transcriptase is a multifunctional enzyme that consists of two domains − An RNA-dependent DNA polymerase domain and A ribonuclease H (RNase H) domain. The ... Read More

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