Immune Response Articles

Major Histocompatibility Complex and MHC Molecules

Anusha Karthik

Updated on 29-Mar-2023 331 Views

Introduction The Major Histocompatibility Complex (MHC) is a group of genes located on chromosome 6 in humans that encode for MHC molecules. These molecules are essential for the immune system to identify and respond to foreign invaders such as viruses, bacteria, and other pathogens. The MHC plays a crucial role in determining the compatibility of transplants and is also implicated in a wide range of diseases, including autoimmune disorders and cancer. Below we shall explore the MHC in detail, discussing its structure, function, and importance in immunology. Structure of MHC Molecules The MHC is divided into two classes: ...